Medium Chain Acyl CoA Dehydrogenase (MCAD) Deficiency

In this video I have explained biochemical mechanism and hallmarks of medium chain acyl coa dehydrogenase deficiency or MCAD deficiency. Medium-chain acyl-CoA dehydrogenase deficiency, often known as MCAD deficiency is a disorder of fatty acid oxidation that impairs the body's ability to break down medium-chain fatty acids into acetyl-CoA. The disorder is characterized by hypoglycemia and sudden death without timely intervention, most often brought on by periods of fasting or vomiting. Prior to expanded newborn screening, MCAD deficiency was an underdiagnosed cause of sudden death in infants. Individuals who have been identified prior to the onset of symptoms have an excellent prognosis. MCAD deficiency is most prevalent in individuals of Northern European Caucasian descent, with an incidence of 1:4000 to 1:17,000 depending on the population. Treatment of MCAD deficiency is mainly preventative, by avoiding fasting and other situations where the body relies on fatty acid oxidation to supply energy. For REGULAR UPDATES you can consider SUBSCRIBING to this channel: https://goo.gl/eMs6rw For short write up of theory on USMLE Biochemistry and other topics on food and nutrition, obesity, weight loss tips you may visit my site: http://www.drmungli.com/ You can follow my Facebook page Biochemistry Made Easy: https://goo.gl/23S9Y7 checkout other awesome channels to learn biochemistry and other subjects from: ThePenguineProf: https://goo.gl/ySNURB Osmosis: https://goo.gl/d1zBs1 Armando: https://goo.gl/jcYwwR Khan Academy: https://goo.gl/7YmIf9 Nucleus Medical Media: https://goo.gl/xdlqsr Trending medical youtube channels: https://goo.gl/nUuJOL 20 useful sites for medical students: https://goo.gl/aPnc19 Biochemistry single line questions site: https://goo.gl/PFCewk

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