Thyroid and parathyroid hormone biosynthesis: biochemistry

Thyroid and parathyroid hormone biosynthesis. In this video, I have discussed an essential mineral Iodine, biosynthesis and regulation of both thyroid and parathyroid hormones. T3 and T4 are the thyroid hormones required for growth and developments and various metabolic processes taking place in our body and they require iodine as one of the mineral and tyrosine as an important amino acid for the iodination. Our dietary iodine trapped by thyroid follicular cells from the capillaries adjacent to the thyroid gland. Then activation of iodine takes place and this process is called oxidation of iodine catalyzed by thyroperoxidase. The next step is iodination which is nothing but the attachment of activated iodine to the tyrosine residues present in thyroglobulin. Thyroglobulin is a glycoprotein synthesized by thyroid follicular cells and released and stored as a colloid in the central space of acini rich in tyrosine residues. After iodination, there is a process called coupling to form T3 and T4 and stored as colloid along with thyroglobulin. [Timestamps] 00:00 Intro 00:53 Iodine sources 02:02 RDA or recommended dietary allowance of iodine 02:17 Iodine metabolism 03:55 Functions of iodine 04:30 Iodine deficiency causes 06:23 Iodine deficiency goiter 06:45 Thyroid gland 07:07 Histology of thyroid follicular cells, parafollicular cells, acini and colloid 08:15 Steps of thyroid hormone synthesis 09:33 uptake of iodine or iodine trapping 11:14 Oxidation of iodine thyroperoxidase 12:39 Iodination tyrosine thyroglobulin monoiodotyrosine and diiodotyrosine MIT and DIT 18:33 Coupling and formation of t3 and t4 rt3 and rt4 20:58 Storage and release of thyroid hormones 23:59 Regulation of thyroid hormone synthesis 24:53 Parathyroid hormone PTH parathyroid gland chief cells 25:26 Synthesis of parathyroid hormone 26:27 Regulation of parathyroid hormone synthesis ionized calcium vitamin d hypocalcemia https://vijayamarakala.com/category/biochemistry/organ-function-tests/liver-function-tests/ Liver function tests: /playlist/PLITxL6KOIm-b2dZapxDPFjs0FKzyo6PTk Diabetes and Insulin: /playlist/PLITxL6KOIm-bBPqs-xnLVnMCO3nID1Rz7 Hemoglobin metabolism: /playlist/PLITxL6KOIm-YOZksTDXgmplYR5GMNxon8 Molecular biology: /playlist/PLITxL6KOIm-a8IZFoGVd5voIn8zRYOvVv Electron transport chain: /playlist/PLITxL6KOIm-YNoCqQtPjZ5Cjm3tEi0YnW Enzymes: /playlist/PLITxL6KOIm-ZMFFdL1Haf2fpaazQuM1eD Digestion and absorption: /playlist/PLITxL6KOIm-ZzciIcbCyHt3wHZbiuDuO1 Carbohydrate chemistry: /playlist/PLITxL6KOIm-ZNbReHKD-S3kpjKAWHXIqG Lipid chemistry: /playlist/PLITxL6KOIm-aO94EbZQSqKTbO1YGeyX2S Protein chemistry: /playlist/PLITxL6KOIm-baCv9fkrnOm_32suZN2UCT Lipid metabolism: /playlist/PLITxL6KOIm-YKYpZS679cCAIKnKQX9-vS Acid-base disorders: /playlist/PLITxL6KOIm-YlQWecLaP0YQRu7Q_H_m96 ABG interpretation: /playlist/PLITxL6KOIm-ZBCRGYTj5bb0QGQ1aK4fRp Bilirubin metabolism: /playlist/PLITxL6KOIm-ZClrGdcDSkpCakLwoHwSrF Vitamins: /playlist/PLITxL6KOIm-Yh6oM0TL9xYk5rFdvGTEbS Bone and cartilage: /watch/xF69yYqriXM2KoWVM8L1wZ-mIOK6LxTILP=tsil&MruW38UNOtpN9 Carbohydrate metabolism: /playlist/PLITxL6KOIm-aWswjKFANjFUOwTpGm_INo Iodine and thyroid hormones: /playlist/PLITxL6KOIm-ZnfrllfWhw5ImiSlko3DVR Acid-base balance: /playlist/PLITxL6KOIm-Zc5kBLwUylhl9-fSoCzF6h Inborn errors of protein metabolism: /playlist/PLITxL6KOIm-aV_wvoJbLQWqdDp5TSoWLS Ketone body metabolism: /playlist/PLITxL6KOIm-ZzQroxjwykI4mGMUlwf1VK Vitamin D: /playlist/PLITxL6KOIm-aED2-s-bl8TmNV_9QAlV0u You can reach me through the following social media links Twitter: https://twitter.com/MarakalaVijaya Linkedin: https://www.linkedin.com/in/vijaya-ma ... Instagram: https://www.instagram.com/vmarakala/ Reddit: https://www.reddit.com/user/vijidr My website: https://vijayamarakala.com #Biochemistry #DrVijayaMarakala tft hyperthyroidism hypothyroidism tpo thyroid cancer study with me

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